The Milstein Chemistry Core Facility provides chemical synthesis and analysis resources and services to the Weill Cornell Medicine community and outside investigators. These services include chemical synthesis for assay development tools and reagents and the confirmatory synthesis of compounds, as well as the chemical analysis of reaction mixtures, extracts and bioassays. The core is near both the Tri-Institutional Therapeutics Discovery Institute and the Molecular Imaging Innovations Institute, allowing for productive sharing of reagents, instruments, knowledge and expertise, and collaborations with researchers interested in drug discovery and molecular imaging.