Publications
Tan C, Cai LQ, Wu W, Qiao Y, Julianne Imperato-McGinley, Chen GQ, and Zhu YS: NSC606985, A novel camptothecin analog, induces apoptosis and growth arrest in prostate tumor cells. Cancer Chemotherapy and Pharmacology, 2008, in press
Qiao Y, Zhang Z-k, Cai LQ, Tan C, Julianne L. Imperato-McGinley and Zhu YS: 17alpha-Estradiol inhibits LAPC-4 prostatic tumor cell proliferation in cell cultures and tumor growth in xenograft animals. Prostate, 67(16):1719-1728, 2007
Yu Y, Wang LS, Shen SM, Xia L, Zhang L, Zhu YS, Chen GQ: Subcellular proteome analysis of camptothecin analog NSC606985-treated acute myeloid leukemic cells. J Proteome Res. 6(9):3808-18, 2007
Butler T, Imperato-McGinley J, Pan H, Voyer D, Cunningham-Bussel AC, Chang L, Zhu YS, Cordero J, Stern E, Silbersweig D. Sex specificity of ventral anterior cingulate cortex suppression during a cognitive test. Human Brain Mapping. 28(11):1206-12, 2007
Liu W, Zhu YS, Guo M, Yu Y, Chen GQ: Therapeutic efficacy of NSC606985, a novel camptothecin analog, in a mouse model of acute promyelocytic leukemia. Leuk Res. 31(11):1565-1574, 2007
Huang Y, Duan QW, Zhu YS Duan YW: In vivo antitumor activity of ZYD88, a Chinese herbal medicine in animal models with S180 sarcoma and Ehrlich tumor. Journal of the Society for Integrative Oncology. 5(2):45-49, 2007
Cohen JK, Cai LQ, Zhu YS and La Perle KM: Pancreaticoduodenal arterial rupture and hemoabdomen in ACI/SegHsd rats with polyarteritis nodosa. Comparative Medicine, 57(4):370-376, 2007
Duan YW, Huang Y, Cai LQ, Duan QW and Zhu YS: The anti-tumor and anti-metastatic effect of a Chinese herbal medicine, ZYD88, in an animal model with the metastatic Lewis lung carcinoma. Oncol Report, 17(6):1391-1397, 2007
Butler T, Pan H, Imperato-McGinley J, Voyer D, Cunningham-Bussel AC, Cordero JJ, Zhu YS, Silbersweig D, Stern E: A network approach to fMRI condition-dependent cognitive activation studies as applied to understanding sex differences. Clinical Neuroscience Research, 6(6):391-398, 2007
Cai LQ, Imperato-McGinley J and Zhu YS: Regulation of prostate 5alpha-reductase isozyme gene expression and prostate weight by dietary fat and caloric intake in the rat. Prostate,66(7):738-748, 2006
Sobel V, Schwartz B, Zhu YS, Cordero J, Imperato-McGinley J: Bone mineral density in the complete androgen insensitivity and 5alpha-reductase-2 deficiency syndromes: evidence for a direct effect of T, but not DHT, on bone strength. J.Clin. Endocrinol. Metab. 91(8):3017-3023, 2006
Butler T, Imperato-McGinley J, Pan H, Voyer D, Cordero J, Zhu YS, Stern E, Silbersweig D: Sex differences in mental rotation: Top down versus bottom up processing. Neuroimage, 32(1):445-56, 2006
Zhu YS, Cai LQ, Huang Y, Fish J, Wang L, Zhang ZK and Imperato-McGinley J: Receptor isoform and ligand specific modulation of DHT-induced PSA gene expression and prostate tumor cell growth by estrogens. J. Androl., 26:500-508, 2005.[Editorial Commentary: Dehm, SM, Tindall DJ: J Androl. 26:509510, 2005]
Song M-G, Gao S-M, Du K-M, Xu M, Yu Y, Wang Q, Chen Z, Zhu YS and Chen G-Q: NSC606985, A camptothecine analog, induces leukemic cell apoptosis through protein kinase Cd-dependent mechanisms. Blood, 105:3714-3721, 2005.
Zhu YS: Molecular basis of steroid action in the prostate. Cellscience Reviews. 1(4):27-55, 2005 (http://www.cellscience.com/journal/journalindex.asp).
Yan H, Wu YL, Jiang Y, Huang Y, Chen Z, Zhu YS, Zhao Q, Chen GQ: Hypoxia-simulating agents and selective stimulation of arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells. Haematologica, 90:1607-1616, 2005
Zhu YS and Sung GF: 5alpha-reductase isozymes in the prostate. J. Med. Sci., 25(1):1-11, 2005.
Zhu YS and Imperato-McGinley J: Pseudohermaphroditism, male, due to 5alpha-reductase-2 deficiency. In: Encyclopedia of Endocrine Diseases, vol. 4, Martinii L et al (eds), Elsevier Inc. San Diego, CA, p131-135, 2004.
Lee J, Zhu YS, Cordero JJ, You X, Cai LQ, Labor L and Imperato-McGinley J: Long-term growth hormone therapy in adulthood results in significant linear growth in siblings with a PROP1 gene mutation. J.Clin. Endocrinol. Metab.,89:4850 4856, 2004.
Sobel V, Zhu YS and Imperato-McGinley J: Fetal hormones and sexual differentiation. Obstet. Gynecol. Clin. N. Am., 31:837-856, 2004
Zhu YS and Imperato-McGinley J: Androgen Insensitivity Syndrome. In: Encyclopedia of Endocrine Diseases, vol. 1, Martinii L et al (eds), Elsevier Inc. San Diego, CA, p214-220, 2004.
Zhu YS, Huang Y, Cai LQ, Zhu J, Duan Y, Duan Q, Imperato-McGinley J: A Chinese medicinal herbal formula, ZYD88 inhibited cell growth and promoted cell apoptosis in prostatic tumor cells. Oncology Reports, 10(5):1633-1639, 2003.
Zhu YS, Cordero JJ, Can S, Cai, LQ, Herrera C, DeFillo-Ricart M and Imperato-McGinley J: Mutations in CYP11B1 gene: phenotype-genotype correlations. Am J Med Genet, 122A(3):193-200, 2003.
Zhu YS, Cai LQ, You X, Cordero JJ, Huang Y and Imperato-McGinley J: Androgen-induced of PSA gene expression is mediated via DHT in LNCaP cells. J. Androl., 24(5):681-687, 2003.
Huang Y, Du, KM, Xue ZH, Yan H, Li D, Liu W, Chen Z, Zhao Q, Tong JH, Zhu YS and Chen GQ: Cobalt chloride and low oxygen tension trigger differentiation of acute myeloid leukemic cells: possible mediation of hypoxia-inducible factor-1alpha. Leukemia, 17:2065-2073, 2003
Zhu YS, Cai LQ, Cordero JJ, Canovatchel WJ, Katz MD and Imperato-McGinley J: A novel mutation in the CAG triplet region of exon 1 of androgen receptor gene causes complete androgen insensitivity syndrome in a large kindred. J. Clin. Endocrinol. Metab., 84:1590 1594, 1999.
Zhu YS, Dellovade TL and Pfaff DW: Interactions between hormonal and environmental signals on hypothalamic neurons: Molecular mechanisms signaling environmental events. Trends Endocrinol. Metab. 8:111-115, 1997
Katz MD, Kligman I, Cai LQ, Zhu YS, Fratianni CM, Neal G, Rosenwaks Z and Imperato-McGinley J: Paternity by intrauterine insemination with sperm from a man with 5alpha-reductase-2 deficiency. N. Engl. J. Med., 336:994-997, 1997.
Zhu YS, Yen PM, Chin WW and Pfaff DW: Estrogen and thyroid hormone interaction on regulation of gene expression. Proc. Natl. Acad. Sci. USA, 93:12587-12592, 1996.
Dellovade TL, Zhu YS, Krey L and Pfaff DW: Thyroid hormone and estrogen interact to regulate behavior. Proc. Natl. Acad. Sci. USA, 93:12581-12586, 1996
Zhu YS, Branch AD, Robertson HD and Inturrisi CE: Cloning and characterization of the hamster proenkephalin gene. DNA Cell Biol., 13:25-35, 1994
Zhu YS, Brodsky M, Franklin SO, Huang TH. and Inturrisi CE: Metrazole induces the sequential activation of c-fos, proenkephalin and tyrosine hydroxylase gene expression in the rat adrenal: Modulation by glucocorticoid and adrenocorticotropic hormone. Mol. Pharmacol., 44:328-336, 1993.
Zhu YS and Szeto HH: Morphine-induced tachycardia in fetal lambs: a bell-shaped dose-response curve, J. Pharmacol. Exp. Ther., 249:78-82, 1989.
