Publications
Du, Y.-C. N. and Stillman, B. (2002). Yph1p, an ORC-interacting protein: potential links between cell proliferation control, DNA replication, and ribosome biogenesis. Cell, 109, 835-848.
Perspectives and comments about this paper:
- Mitchell, A. (2002). DNA replication: a complex landing, Nature Reviews Molecular Biology, 3, 550.
- LeBrasseur, N. (2002). Coordination of replication, Journal of Cell Biology, 158, 385.
- Sadler, K. C. (2002). Ribosome assembly reawakens, Trends in Cell Biology, 12, 411.
Varmus, H., Pao, W., Politi, K., Podsypanina, K., and Du, Y.-C. N. (2005). Oncogenes come of age. Cold Spring Harbor Symposia on Quantitative Biology, 70, 1-9.
Du, Y.-C. N.*, Lewis, B., Hanahan, D., and Varmus, H. (2007). Assessing Tumor Progression Factors by Somatic Gene Transfer into a Mouse Model: Bcl-xL Promotes Islet Tumor Cell Invasion. PLoS Biology, 5, 2255-2269. (*corresponding author)
Research highlights about this paper:
- Stevens, K. (2008). There is a virus going around. Nature Methods, 5, 6-7.
Podsypanina, K., Du, Y.-C. N., Jechlinger, M., Beverly L. J., Hambardzumyan, D., and Varmus, H. (2008). Seeding and propagation of untransformed mouse mammary cells in the lung. Science, 321, 1841-1844.
Preview about this paper:
- Weinberg, R.A. (2008). Leaving home early: reexamination of the canonical models of tumor progression. Cancer Cell, 14, 283-284.
Du, Y.-C. N.*, Klimstra, D., and Varmus, H. (2009). Conditional activation of PyMT in beta cells induces irreversible benign b-cell hyperplasia but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitor cells. PLoS ONE, 4, e6932. (*corresponding author)
Reddy, J.P., Peddibhotla, S., Bu, W., Zhao, J., Haricharan, S., Du, Y.-C. N., Podsypanina, K., Rosen, J. M., Donehower, L. A., and Li, Y. (2010). ATM-dependent apoptosis and senescence are activated in somatic mammary cells following ErbB2-induced aberrant proliferation. PNAS, 107, 3728-3733.
Du, Y.-C. N.*, Chou, C.-K., Klimstra, D., and Varmus, H.* (2011). Receptor for hyaluronan-mediated motility isoform B promotes liver metastasis in a mouse model of multistep tumorigenesis and a tail vein assay for metastasis. PNAS, 108, 16753-16758. (*corresponding author)