Menell JS, GM Cesarman, A Jacovina, MM McLaughlin, E Lev, KA Hajjar. Annexin II and Bleeding in Acute Promyelocytic Leukemia, N. Engl. J. Med., 340:994-1004, 1999.
Jacovina AT, F Zhong, E Khazanova, E Lev, AB Deora, KA Hajjar. Neuritogenesis and the Nerve Growth Factor-Induced Differentiation of PC-12 Cells Requires Annexin II-Mediated Plasmin Generation, J. Biol. Chem., 276: 49350-49358, 2001.
Deora AB, G Kreitzer, AT Jacovina, KA Hajjar. An Annexin 2 Phosphorylation Switch Mediates p11-Dependent Translocation of Annexin 2 to the Cell Surface, J. Biol. Chem., 279:43411-43418, 2004.
Ling Q, AT Jacovina, AB Deora, M Febbraio, R Simantov, R Silverstein, B Hempstead, W Mark, KA Hajjar. Annexin II is a Key Regulator of Fibrin Homeostasis and Neoangiogenesis, J. Clin. Invest., 113:38-48, 2004.
Brownstein , AB Deora, AT Jacovina, R Weintraub, M Gertler, KM Faisal Khan, DJ Falcone, KA Hajjar. Annexin II Mediates Plasminogen-Dependent Matrix Invasion by Human Monocytes, Enhanced Expression by Macrophages, Blood, 103: 317-324, 2004.
Krishnan S, AB Deora, JP Annes, J Osoria, DB Rifkin, KA Hajjar. Annexin II-Mediated Plasmin Generation Activates TGF-ß3 During Epithelial-Mesenchymal Transformation in the Developing Avian Heart, Dev. Biol. 265:140-154, 2004.
Ballard, VLT, A Sharma, I Duignan, JM Holm, A Chin, R Choi, KA Hajjar, SC Wong, JM Edelberg. Vascular Tenascin-C Regulates Cardiac Endothelial Phenotype and Neovascularization, FASEB J. 20:717-719, 2006.
Cesarman-Maus G, NP Rios-Luna, AB Deora, R Villa , M Cravioto, D Alarcon-Segovia, J Sanchez-Guerrero, KA Hajjar. Autoantibodies against the Fibrinolytic Receptor, Annexin 2, in Antiphospholipid Syndrome, Blood107: 4375-4382, 2006.
He, K-L, AB Deora, H Xiong, Q Ling, BB Weksler, R Niesvizky, KA Hajjar. Annexin A2 Regulates Ubiquitination and Degradation of S100A10/p11. J. Biol. Chem., 283:19192-19200, 2008.
Jacovina, AT, AB Deora, Q Ling, MJ Broekman, D Almeida, C Greenberg, AJ Marcus, JD Smith, KA Hajjar. "Homocysteine Inhibits Neoangiogenesis through Blockade of Annexin A2-Dependent Angiogenesis," J. Clin. Invest. 119:3385-3394, 2009.
Zhu, H, X Fan, J Liu, Y Murata, Z Yu, J Lu, KA Hajjar, EH Lo, X Wang. "Annexin A2 Combined with Low Dose tPA Improves Thrombolytic Therapy in a Rat Model of Focal Embolic Stroke," J. Cerebral Blood Flow Metab. 30:1137-46, 2010.
Ruan J, P Martin, M Coleman, R Furman, K Cheung, A Faye, R Elstrom, M Lachs, KA Hajjar, JP Leonard. "Durable Responses with the Metronomic Regimen RT-PEPC in Elderly Patients with Recurrent Mantle Cell Lymphoma," Cancer, 116:2655-2664. 2010.
Cesarman-Maus G, C Cantú-Brito, F Barinagarrementeria, R Villa, E Reyes, J Sanchez-Guerrero, KA Hajjar, EG Latorre. "Autoantibodies Against the Fibrinolytic Receptor, Annexin A2, in Cerebral Venous Thrombosis," Stroke 42:501-503, 2011.
He K, G Sui, H Xiong, MJ Broekman, B Huang, AJ Marcus, KA Hajjar. "Feedback Regulation of Endothelial Cell Surface Plasmin Generation by PKC Dependent Phosphorylation of Annexin A2," J. Biol. Chem. 286:15428-15439, 2011.
Huang B, AB Deora, K He, K Chen, A Jacovina, G Sui, D Almeida, P Hong, P Burgman, KA Hajjar. "Hypoxia-Inducible Factor-1 Drives Annexin A2 System-Mediated Perivascular Fibrin Clearance in Oxygen-Induced Retinopathy in Mice," Blood 118: 118:2918-2929, 2011.
Zhai H, S Acharya, I Gravanis, S Mehmood, RJ Seidman, KR Shroyer, KA Hajjar, S Tsirka. "Annexin A2 Promotes Tumor Progression in Glioma Cells," J. Neurosci. 31:14346-14360, 2011.
Education
M.D.,
The Johns Hopkins University School of Medicine,
1978