Research Overview
Microarray-based gene expression and SNP analysis
The high resolution and high through-put microarray technology has made a significant impact on biomedical research. Studying gene expression utilizing microarrays allows scientists to survey the expression of thousands of genes simultaneously under numerous conditions and in some cases study the expression of all genes at once for organisms whose genome has been substantially characterized. DNA microarray technologies support genetic mapping studies and mutational analyses as well as genome-wide monitoring of gene expression, and are becoming increasingly more common tools in research and clinical applications. In December 2000, Weill Medical College (WMC) launched a Microarray Core Facility (MCF) to provide services in both the Affymetrix GeneChip array system and custom-arraying to the WMC and New York Presbyterian Hospital (NYPH) communities. The current MCF provides a full-range of services from performing microarray experiment to data management and delivery, and helps researchers explore biological questions systematically with this high throughput technology at lower costs, greater flexibility and simplicity, coupled with efforts to maximize the extraction of biologically meaningful data interpretation.
