Charles E. Inturrisi, Ph.D.

• Research
• Honors & Awards
• Biography
• Publications

Publications

• Inturrisi, C.E. and Gregus, A.M. Mechanisms of Opioid Tolerance, in The Eighth IASP Research Symposium :A Global Problem: Cancer Pain from the Laboratory to the Bedside, R. Bell,E. Kalso, J. Paice and O. Soyannwo, editors, Chapter 7,123-139, 2010.
• Chapman CR, Lipschitz DL, Angst MS, Chou R, Denisco RC, Donaldson GW, Fine PG, Foley KM, Gallagher RM, Gilson AM, Haddox JD, Horn SD, Inturrisi CE, Jick SS, Lipman AG, Loeser JD, Noble M, Porter L, Rowbotham MC, Schoelles KM, Turk DC, Volinn E, Von Korff MR, Webster LR, Weisner CM. Opioid Pharmacotherapy for Chronic Non-cancer Pain: A Research Guideline for Developing an Evidence-Base. J Pain. 2010 Sep;11(9):807-29.
• Gregus AM, Inra CN, Giordano TP 3rd, Costa AC, Rajadhyaksha AM, Inturrisi CE. Spinal mediators that may contribute selectively to antinociceptive tolerance but not other effects of morphine as revealed by deletion of GluR5. Neuroscience. 2010 Aug 11;169(1):475-87.
• Weyerbacher, A. R., Xu , Q., Tamasdan, C., Shin, S. and Inturrisi, C.E. The N-Methyl-D-Aspartate Receptor (NMDAR) independent maintenance of inflammatory pain. Pain, 148:237-246,2010.
• Bogulavsky, J.J., Gregus, A.M., Kim, P. T.-H, Costa, A.C.S., Rajadhyaksha, A.M. and Inturrisi, C.E.: Deletion of the GluR5 subunit of kainate receptors affects the development of morphine tolerance. J Pharmacol Exp Ther.,328(2):579-587, 2009.
• Garraway, S.M., Xu. Q.,and Inturrisi, C.E. siRNA-mediated knockdown of the NR1 subunit gene of the NMDA receptor attenuates formalin-induced pain behaviors in adult rats. J. Pain 2009 Apr;10(4):380-390.
• Xu, Q., Garraway, S.M., Weyerbacher , A.R., Shin, S. J. and Inturrisi, C. E.: Activation of the neuronal extracellular signal-regulated kinase 2 (ERK2) in the spinal cord dorsal horn is required for CFA-induced pain hypersensitivity. J. Neurosci., 28:14087-14096, 2008.
• Hsinlin T Cheng, H.T., Suzuki, M., Hegarty D.E., Xu Q., Weyerbacher, A., R., South S.M., Ohata M. and Inturrisi C.E. Inflammatory pain-induced signaling events following a conditional deletion of the N-Methyl-D-Aspartate receptor in spinal cord dorsal horn. Neuroscience 155(3):948-58, 2008.