Seminars and Symposiums

Each month the Judith Jaffe Multiple Sclerosis Center hosts the Monthly Multiple Sclerosis Research Symposia. Through this program, a highly recognized scientist in the field of multiple sclerosis (MS) is invited to present their current research. Participants, both clinicians and scientists, have the opportunity to meet with the invited speakers and members of the Judith Jaffe MS Center at the pre-lecture reception and are actively encouraged to participate in the dialog following each lecture. Topics include neurobiology, neuroimmunology, genetics, neuroimaging, and therapeutic advancements.

Statement of Need

Multiple Sclerosis (MS) is a complicated disease by virtue of the fact that it primarily involves an interaction between the central nervous system and the immune system, the two most complicated organ systems in the body. Advancements in cellular biology, molecular biology, systems biology, informatics, imaging, pharmacology and biologics as they relate to neurology, immunology and MS, occur at a rapid pace.

Target Audience

This lecture series is designed to provide a venue for neurologists and researchers interested in MS where they will be presented with the latest topics and scientific advancements in MS.

Course Goal and Objectives

Participants should be able to have an increased understanding of:

  1. The pathophysiologic mechanisms thought to be functioning in MS that lead to irreversible disability.
  2. The mechanism by which therapeutics work in MS and the importance of early intervention.
  3. The tools used in diagnosis and monitoring of disease activity including MRI, serum profiling, CSF profiling, and genetic susceptibility.
  4. The topics of regeneration and repair in MS that are often raised by patients.
  5. The immunologic and neuroscientific methods used to study MS.


6:00–6:45pm Registration and Reception

6:45–7:00pm Welcome and Introduction

7:00–7:55pm Lecture by Guest Speaker

7:55–8:10pm Question and Answer Session

8:10–8:15pm Concluding Remarks/Adjourn

Schedule of Lectures and Faulty Speakers

January 18, 2011

The Myelin Water Fraction in Normal and Multiple Sclerosis Central Nervous System Tissue

Alexander MacKay,MD
Professor of Physics and Astronomy and Radiology
Director of the University of British Columbia MRI
Research Centre

February 15, 2011

Towards CNS Protection and Repair in Multiple Sclerosis

Garth R. John, PhD
Associate Professor of Neurology
Corinne Goldsmith Dickinson Center for Multiple Sclerosis
Mount Sinai School of Medicine

March 8, 2011

Axonal Pathology in MS:Who, what, and where? A novel treatment for MS

Bruce Trapp, PhD
Chairman, Department of Neurosciences
Lerner Research Institute
The Cleveland Clinic Foundation

April 20, 2011

CNS Remyelination: from biology to therapy

Robin Franklin, PhD
Professor of Neuroscience
Director, MRC Cambridge Centre for Stem Cell Biology
and Regenerative Medicine and Department of
Veterinary Medicine University of Cambridge

May 10, 2011

Neural Stem Cells in Promoting Tissue Repair in a Viral Model of Demyelination

Thomas E. Lane, PhD Professor and Chancellor's Fellow
Department of Molecular Biology and Biochemistry
Associate Director, Institute for Immunology
University of California, Irvine

June 14, 2011

Imaging Mechanisms of Neuro-axonal Damage in MS

Matilde Inglese,MD, PhD
Associate Professor of Radiology,
NYU Langone Medical Center

September 20, 2011

The Role for the Chemokine CXCL12 in CNS Protection and Repair during Demyelinating Disease

Robyn Klein,MD, PhD
Associate Professor of Internal Medicine
Pathology and Immunology
Anatomy and Neurobiology
Washington University of St. Louis

October 25, 2011

Bring Your Best Patient Case - Case Review

Moderated by Susan Gauthier, DO, MPH
Location Moved to:
1300 York Avenue (at 69th Street)
Weill Auditorium - 2nd Floor
Please email case studies for review/discussion to

Monday, November 14, 2011

Update on Pediatric MS

Lauren Krupp, MD
Co-Director, National Pediatric MS Center
Co-Director, Comprehensive MS Center
SUNY Stony brook University

Location Moved to:
1300 York Avenue (at 69th Street)
Weill Auditorium - 2nd Floor

December 13, 2011

Microglia: new concepts and markers

Richard Ransohoff, MD
Director of the Neuroinflammation Research Center,
Lerner Research Institute, Cleveland Clinic
Professor of Molecular Medicine at the Cleveland Clinic
Lerner College of Medicine at Case Western Reserve University
Staff Neurologist in the Mellen Center for Multiple
Sclerosis Treatment and Research, Cleveland Clinic


Susan A. Gauthier, DO, MPH
Assistant Professor of Neurology
Judith Jaffe Multiple Sclerosis Center
Weill Cornell Medical College

Timothy K. Vartanian, MD, PhD
Director, Judith Jaffe Multiple Sclerosis Center
Department of Neurology
Weill Cornell Medical College

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