biochemist and culture

Development and function of the nervous system is a unifying theme of the Neuroscience PhD program at Weill Cornell Graduate School (WCGS). Students interact closely with faculty studying the nervous system from a wide variety of scientific disciplines, including molecular genetics, biochemistry, pharmacology, neuroanatomy, electrophysiology, and computational and systems neuroscience. They work at the molecular, cellular, and organism systems, ranging from insects to rodents to human and non-human primates.


Focus areas in the program of study include: neural disease, synaptic transmission, developmental neurobiology and regeneration, vision, computational and systems neuroscience, and neuropharmacology.

The nearly 50 faculty members in the program come from Weill Cornell Medical College (WCMC), Sloan-Kettering Institute (SKI, part of Memorial Sloan-Kettering Cancer Center), and Burke-Cornell Medical Research Institute.

The research interests of the program cover the entire range of neuroscience, including the regulation of neural development, neuronal plasticity, control of neurotransmitter synthesis and release, learning, the response of neurons and neural tissue to injury, the regulation of gene expression, endocrine function, circuit development, vision and other sensory systems, information processing, and behavior.


The basic science of developmental neurobiology explores the elementary processes by which the brain forms (morphogenesis), structure is established (histogenesis), neuronal and glial subtypes are specified from progenitors, connections are established and operate. Discoveries about the way that neurons form and communicate make this field one of the most promising routes toward increasing our understanding of the brain and mind. Genetics research in neurology and psychiatry is an exciting, rapidly advancing field that looks at the etiology of disease, as well as works to identify genetic predictors of disease, likely response to available treatment, and avenues to new therapies. Studies of epigenetic effects are opening a new perspective on "nature versus nuture" issues in brain development at the molecular level.


Development and function of the nervous system as a unifying theme of the Neuroscience program is reflected in the work at The Sackler Institute for Developmental Psychobiology. This institute is engaged in research on typical and atypical brain development. A primary objective is to use new techniques to study developing children in order to transform clinical methods. The Institute's program of research and training emphasizes functional neuroimaging, and genetic and behavioral influences on cognitive and emotional development. The Institute is both wide ranging and influential in its technical approaches to the study of children and has become one of the best research centers in the world for the neurocognitive study of children.


Research is also ongoing in the fields of cerebrovascular physiology, cerebral ischemia, cellular and system neurophysiology, cellular and molecular neurobiology, neuroanatomy at the light and ultrastructural level, and imaging.

Translational research links many of the areas of basic science to clinical problems. Particular translational areas include studies in humans with brain injury, neural tube defect (spina bifida, anencephaly) and cortical malformations, neurodegenerative diseases, epilepsy, neuroimmunological, and behavioral disorders.


Many members of the program have a special interest in questions that are particularly relevant to human disease, and their research has important implications for topics such as stem cell therapeutics, the regulation of pain, neurodegenerative diseases such as Alzheimer's and Parkinson's disease, neural tumors, stroke, addiction, aging, brain malformations, epilepsy, autism, and neuropsychiatric illnesses.


Prospective students interested in combining the strengths of the Field of Psychology and Cognitive Science at Cornell University in Ithaca, New York with the Neuroscience program in Manhattan are encouraged to consider the IMAGINE program (Ithaca Manhattan Graduate Initiative in Neuroscience). In Ithaca, the program specializes in basic analysis of perception, cognition, communication and decision making, grounded in developmental and evolutionary perspectives, with a strong computational emphasis. Weill Cornell provides an outstanding research facility for investigation of the development, structure, and function of the nervous system, using a wide variety of scientific disciplines including pharmacology, neuroanatomy, electrophysiology, imaging, and genomic and transgenic approaches within animal models and specific clinical populations. IMAGINE students receive exceptional training in both how to choose and design research questions and how to apply this skill in clinical settings with the most current and powerful techniques. Learn about the program, its faculty and application procedures on the IMAGINE web site.

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