During the fourth year, student correlate their preceding medical school experiences and begin to function effectively in the physician's role while sharpening their clinical skills in preparation for residency training. Students are required to complete sixteen weeks of elective courses, a four-week sub internship in either General Medicine or General Pediatrics, the Advanced Biomedical Sciences course, and four additional credit weeks in Advanced Biomedical Sciences (see below).

The Advanced Biomedical Sciences course is offered during the last four weeks of the fourth year, just prior to graduation. This course, both a return to the basic sciences and "The Last Hurrah," covers the latest advances in biomedical science and technology currently applied to the practice of medicine including topics particularly germane to frontline medical practice. The Spring of 2000 course will address receptor biology, congenital disease, drug resistance, angiogenesis, cancer biology, arteriosclerosis, neurologic disease and immune responses.

The other four credit weeks consist of fulltime basic science research, a research tutorial or a teaching experience in a basic science course.