Core Courses

Photo by: Sara Cavic

The core curriculum consists of 22 credits focusing on a variety of topics related to clinical and translational research. Completion of these 22 credits is required for both the Certificate and Master’s programs in Clinical and Translational Research.

Index

Detailed List

Bioinformatics Workshop
(1 credit)
Instructor(s):
Lucy Skrabanek, Ph.D.
Email: las2017@med.cornell.edu
Phone: (646) 962-5634

Description:
This focus of this workshop is on web-based bioinformatics tools. At the end of the course, trainees will be expected to have a solid foundation in the use of the fundamental tools of bioinformatics and how they apply to clinical and translational investigation.

Introduction to Biostatistics in Clinical Research
(2 credits)
Instructor(s):
Paul Christos, DrPH, MS, MPH
Email: pac2001@med.cornell.edu
Phone: (646) 962-8018

Description:
This course is an introduction to the fundamental statistical issues in the design of clinical research studies.  Its primary emphasis is on understanding the design and analytic methods of clinical research from a statistical perspective.  Lectures and discussions will focus on the following: exploratory data analysis; basic concepts of statistical analysis; construction of hypothesis tests and confidence intervals; the development of statistical methods for analyzing data; development of mathematical models used to relate a response variable to explanatory or descriptive variables; and an introduction to statistical analysis of microarray and genomic studies.

Clinical Trials Design and Analysis
(2 credits)
Instructor(s):
Marshall Glesby, M.D., Ph.D.
Email: mag2005@med.cornell.edu
Phone: (212) 746-7134 

Timothy Wilkin, M.D., M.P.H
Email: tiw2001@med.cornell.edu

Description:
This course will provide an overview of how to design, conduct, and analyze clinical trials.  Completion of this course will lead to an understanding of the theoretical and practical aspects of clinical trials related to the strengths and limitations of randomized clinical trials; theoretical and practical aspects of randomization, stratification, and blinding; challenges of designing and implementing single center and multi-center clinical trials; major issues in the analysis of clinical trials; role of clinical trials in the drug development process; and investigator’s roles and responsibilities in conducting clinical trials.

Data Management for Clinical Research
(2 credit)
Instructor(s):
Elizabeth Wood, B.S., M.S.
Email: eawood@med.cornell.edu
Phone: (212) 746-4744

Description:

This course is designed to familiarize individuals with computer technologies and procedures essential in current clinical research, and will cover practical topics such as creating research databases, safeguarding patient confidentiality, regulatory issues, data and file system security, data transfer over networks, and backup systems.  In addition, it will cover basic concepts in medical informatics essential for data sharing including principles of database design, medical vocabularies, data standards, data warehousing, and Internet technologies.

Ethical, Social and Legal Issues in the Responsible Conduct of Research
(1 credit)
Instructor(s):
Inmaculada de Melo-Martin, PhD, MS
Email: imd2001@med.cornell.edu
Phone: (646) 962-8031

Description:
This course is part of a two-part series designed to heighten students’ awareness to ethical considerations relevant to conducting research. It will inform trainees of federal, state, and institutional policies, regulations, and procedures, and provide trainees with critical analysis and problem-solving skills for ethical decision-making. The first component is an eight-week internet-based course offered in the fall term. The first part, Tri-Institutional Responsible Conduct of Research, is offered during the fall semester.

Foundations of Clinical Research
(3 credits)
Instructor(s):
Alvin Mushlin, M.D.
Email: aim2001@med.cornell.edu
Phone: (212) 746-3587

Description:
The goal of this course is to provide an overview of the methodological foundations for research involving human subjects, while gaining an understanding of core epidemiological concepts, theory and applications of commonly used biostatistical methods, and investigative methods of clinical interventions.

Foundations of Epidemiology
(3 credits)
Instructor(s):
Patricia Cassano, M.P.H., Ph.D.
Email: pac6@cornell.edu
Phone: (607) 255-6586

Description:
This course is designed to train students to conduct epidemiologic research of the highest quality.  Through a combination of video-conferencing and live lectures and in-class questions/answers discussion sessions, students will learn how to evaluate research conducted by others and how to apply epidemiologic principles to health-related specialties including clinical medicine and health services.  The course will provide students with an introduction to basic and intermediate epidemiologic methods to build the foundation for further work in epidemiology either as practicing epidemiologists or as sophisticated users of epidemiologic information.

Grant Writing and Scientific Journalism:  Inspiration, Writing, and Education
(2 credits)
Instructor(s):
John Wagner, Ph.D.
Email: jawagne@med.cornell.edu
Phone: (212) 746-6586

Sushmita Mukherjee, Ph.D., M.S.
Email: smukherj@med.cornell.edu
Phone: (212) 746-6490

Description:

This course will focus on strengthening scientific writing skills.  Students will develop and write a formal research proposal in an area of personal interest; write an article for a scientific journal; critically evaluate the merits of specific approaches to scientific problems and compose formal critiques; and develop an article that effectively presents scientific work to the general public.

Molecular Biology and Genetics in Clinical Research
(2 credits)
Instructor(s):
Yuan-Shan Zhu, M.D., Ph.D.
Email: yuz2002@med.cornell.edu
Phone: (212) 746-8348

Description:
The aim of this course, composed of both lectures and workshops, is to introduce the following: basic concepts and principles of molecular biology and molecular genetics; basic technology of molecular biology in translational research; contemporary concepts and technology of molecular genetics and molecular biology as related to clinical research and clinical medicine. Topics will include the human genome, gene structure, gene expression, gene mutations, gene interference, gene cloning, gene therapy, and animal models of human diseases. Both basic and contemporary technologies will be covered, including DNA, RNA and protein isolation, DNA amplification, mutation detection, mRNA and protein determination, microarray, proteomics, and data base searching.

Principles of Clinical Pharmacology
(2 credits)
Instructor(s):
Marcus Reidenberg, M.D.
Email: mmreid@med.cornell.edu
Phone: (212) 746-6227

Description:
This course is designed to present basic principles for understanding the rationale behind development of drug therapy with consideration of the factors involved in individual variability, pharmacokinetics, and pharmacogenomics.  Topics will include:  dose-response, drug efficacy and potency, drug absorption, distribution, metabolism and excretion, drug addiction, drug use in pregnancy, chemotherapy, and the principles behind drug-to-drug interactions.

Research Grant Writing
(1 credit)
Instructor(s):
Amy Markowitz, JD

Description:
This course provides an introduction to the basic skills, principles and techniques of successful grant writing and gives students understanding of the fundamental components of a grant proposal such as the abstract or summary, background and significance, specific aims/goals and objectives, as well as project design and methods so they can develop competitive grant proposals. Students will workshop draft grant proposals among peers and in one-on-one tutorials.

Tri-Institutional Responsible Conduct of Research (on-line course)
(1 credit)
Instructor(s):
Mary Simmerling, PhD
Email:  mcs2006@med.cornell.edu
Phone: (212) 821-0612

Helene Brazier-Mitouart, PhD
Email: heb2020@med.cornell.edu
Phone: (646) 962-6204

Description:
This course is part of a two-part series designed to heighten students’ awareness to ethical considerations relevant to conducting research. It will inform trainees of federal, state, and institutional policies, regulations, and procedures, and provide trainees with critical analysis and problem-solving skills for ethical decision-making. The first component is an eight-week internet-based course offered in the fall term. The second part, Ethical, Social and Legal Issues in the Responsible Conduct of Research, is offered during the summer semester.