Accessing General Core Laboratory Resources

Inquiries:

Application process:

  1. If you are requesting core lab services only, or core lab in combination with molecular core and/or biostatistics, use our Expedited Application for Biostatistics and/or Core Lab.
  2. Otherwise, if your study has been externally peer-reviewed and approved, use our Expedited Application for Externally Peer-Reviewed and Approved Studies.
  3. All others, please use our Full Research Application.

Related links:

General Core Laboratory

The General Core Laboratory, operated and funded through the CTSC, develops and carries out research-related sample analyses to investigators from any of the CTSC partner institutions. Current and prospective clinical and translational investigators are encouraged to inquire about any assay or analytical technique that may prove useful in their research. The experienced staff of the Core Lab can work with investigators to prepare and test new assays for use. The core laboratory is licensed by the New York State Department of Health.

Services Offered

  • Sample processing and storage: The core lab processes not only the samples assayed in the core lab, but also samples sent to outside labs for analysis. Samples processed in the core lab include blood, urine, saliva, and cells. The samples will be stored in the core lab for up to 2 years for those samples assayed in the core lab, and up to 6 months for those samples sent to outside labs.
  • Bulk immunodiagnostic and chemical assays: This enables planning of multiple sample-per-patient studies where instrumentation issues, sample size or precision requirements make performance of assays elsewhere impractical. Please refer to the list of core laboratory assays for tests that are currently offered in the online application system. If you need a specific assay not on the list, please contact Sandra Aranibar-Atristain or Dr. Yuan-Shan Zhu.
  • Various assays for cell biology including cell count & viability, cell proliferation, cell apoptosis, cell cycle, DNA damage, autophagy, etc.
  • Letters of support for grant applications.
  • Multiplex assay instrument (SECTOR Imager 2400). Please click here for more information.
  • ChemiDoc MP imaging system. Please click here for more information.

Available Equipment

  • SECTORTM Imager 2400 Multiplex Assay Instrument
  • Bio-Rad ChemiDoc MP imaging system
  • ChemWell 2910 system
  • VICTOR3 Multilabel Reader
  • COBRA Auto-Gamma Radiation Counter
  • Liquid Scintillation Counter
  • WALAC Plate-reading Time-Resolved Fluorometer
  • Fomos and A Waters HPLC with electrochemical detection, binary gradient pumping, microbore (<1 mm diameter) columns and UV detector
  • Varian Gas Chromatograph-Mass Spectrometers (GC-MS)
  • Bio-Rad Protean 2-Dimensional Gel Electrophoresis System for protein separation and sample preparation for proteomics
  • Chronolog700 4-Clot Detection System used for assays of certain blood coagulation factors that cannot be measured by standard immunodiagnostic methods
  • STart® 4 semi-automated hemostasis analyzer from Diagnostica Stago for electro-mechanical clot detection (PT, APTT, Fibrinogen, Thrombin Time, Reptilase Time, Factors II, V, VII, VIII, IX, X, XI, XII, Protein C & S Activity, PTT-lupus assay, Staclot LA, VIIa-rTF
  • DCA2000+ Analyzer for plasma hemoglobin A1c and urinary albumin/creatinine tests
  • Cholestech LDX Analyzer for the measurement of blood lipid profile plus glucose and ALT
  • Two Eppendorf Mastercycler Thermal Cyclers
  • Multiple -20 and -70 Freezers, and centrifuges

Examples of Available Assays

(assay development may be possible for new tests not in this list)

  • 1,25-Vitamin D
  • 11-Deoxycortisol
  • 17alpha-OH-Progesterone
  • ACTH
  • Activated PTT (APTT)
  • Activation Regulated Chemokine
  • Androstenedione
  • Anti-beta-2-glycoprotein I IgM
  • Anti-beta2-glycoprotein I IgG
  • Anti-Cardiolipin IgA
  • Anti-Cardiolipin IgG
  • Anti-Cardiolipin IgM
  • Anti-phosphatidyl Serine IgA
  • Anti phosphatidyl Serine IgG
  • Anti-phosphatidyl Serine IgM
  • Bone-Alkaline Phosphatase
  • C-peptide
  • Catecholamine
  • CCL18/PARC (Human Pulmonary)
  • Cholesterol-total
  • CloFAL
  • Cortisol (Saliva)
  • Cortisol (Serum)
  • Cortisol (Urine)
  • C-peptide
  • Creatinine (Urine)
  • C-Reactive Protein (CRP)
  • D-dimer
  • DHEA
  • DHEA-S
  • Dihydrotestosterone (DHT)
  • Enzygnost F1/2
  • Estradiol
  • Estrone
  • Factor 8,9,11
  • FSH
  • Growth Hormone
  • Ghrelin (Total)
  • Glucose
  • HbA1c
  • HDL
  • IFN-gamma
  • IGF-1
  • IGF-BP1
  • IGF-BP3 IL-1-beta
  • IL-1Ra
  • IL-2
  • IL-6
  • IL-8
  • IL-10
  • Insulin
  • Leptin
  • Leukotriene-B4
  • LH
  • Microalbumin (urine)
  • NT-proBNP
  • NTx
  • Osteo-protegerin
  • Osteocalcin
  • Oxytocine
  • PINP
  • Pregnenolone
  • Pro-insulin
  • Progesterone
  • Prolactin
  • Prostaglandin-E2
  • Protein S
  • Protein Z
  • Prothrombin Time (PT)
  • PTH (intact)
  • SDF-1alpha
  • SHBG
  • Soluble TNF Receptor II (sTNF-RII)
  • sRANKL
  • TAT
  • Testosterone (free)
  • Testosterone (total)
  • TGF-beta
  • Tissue Factor
  • TNF-alpha
  • Triglyceride
  • TSH
  • TSP-1
  • VEGF